Publications

1. Franz T#, Negele J#, Kahlfuss S*Cytotoxic innate lymphoid cells sense tumor-derived IL-15: A novel mechanism

of cancer immunosurveillance. 

Signal Transduction and Targeted Therapy. 2022. Accepted. *Corr. author  #First-authors

2. Wang Y-H#, Noyer L#, Kahlfuss S#, Raphael D, Tao AJ, Kaufmann U, Zhu J, Mitchell-Flack M, Sidhu I, Zhou F, Vaeth M, Thomas PG, Saunders SP, Stauderman K, Curotto de Lafaille MA, Feske S*. Distinct roles of ORAI1 in T cell-mediated allergic airway inflammation and immunity to influenza A virus infection.

Science Advances. 2022. In press. *Corr. author #First-authors  

 

3. Böttcher-Loschinski R*, Rial Saborido J, Böttcher M, Kahlfuss S, Mougiakakos D. Lipotoxicity as a Barrier for T Cell-Based Therapies. Biomolecules. 2022; 12(9):1182. https://doi.org/10.3390/biom12091182 *Corr. author 

4. Böttcher M*, Böttcher-Loschinski R., Kahlfuss S., Aigner M., Gießl A., Mackensen A., Schlötzer-Schrehardt U., Tüting T., Bruns H. and Mougiakakos D*. *Corr. authors CLL-Derived Extracellular Vesicles Impair T-Cell Activation and Foster T-Cell Exhaustion via Multiple Immunological Checkpoints. Cells. 2022. https://doi.org/10.3390/cells11142176 *Corr. authors

5. Thurm C.#, Reinhold A.#, Borucki K., Kahlfuss S., Feist E., Schreiber J., Reinhold D., and Schraven B*. Homologous and Heterologous Anti-COVID-19 Vaccination Does Not Induce New-Onset Formation of Autoantibodies Typically Accompanying Lupus Erythematodes, Rheumatoid Arthritis, Celiac Disease and Antiphospholipid Syndrome. 

Vaccines. 2022. https://doi.org/10.3390/vaccines10020333  *Corr. author  #First-authors 

6. Krone A.#, Fu Y.#, Schreiber S.#, Kotrba J., Borde L. Nötzold A., Thurm C., Negele J., Franz T., Stegemann-Koniszewski S., Schreiber J., Shukla A., Geffers R., Schraven B., Reinhold D., Dudeck A., Reinhold A., Müller A., and Kahlfuss S*.

Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc. Scientific reports. 2022. doi: 10.1038/s41598-022-04827-6 *Corr. author, #First-authors 

7. Mougiakakos D and Kahlfuss S*. 

“Moonlighting” at the power plant: how mitochondria facilitate serial killing by CD8+ cytotoxic T cells.  

Signal Transduction and Targeted Therapy. 2021. https://doi.org/10.1038/s41392-021-00846-3. *Corr. author

8. Formaglio P, Alabdullah M, Siokis A, Handschuh J, Sauerland I, Fu Y, Krone A, Gintschel P, Stettin J, Heyde S, Mohr J, Philipsen L, Schröder A, Robert PA, Zhao G, Khailaie S, Dudeck A, Bertrand J, Späth GF, Kahlfuss S, Bousso P, Schraven B, Huehn J, Binder S, Meyer-Hermann M, Müller AJ.

Nitric oxide controls proliferation of Leishmania major by inhibiting the recruitment of permissive host cells.

Immunity. 2021 Oct 15:S1074-7613(21)00406-4. doi: 10.1016/j.immuni.2021.09.021. Epub ahead of print. PMID: 34687607.

9. Thurm C, Schraven B, Kahlfuss S*.

ABC Transporters in T Cell-Mediated Physiological and Pathological Immune Responses.

Int J Mol Sci. 2021 Aug 25;22(17):9186. doi: 10.3390/ijms22179186. PMID: 34502100; PMCID: PMC8431589. *Corr. author

10. Schreiber S, Hammers CM, Kaasch AJ, Schraven B, Dudeck A, Kahlfuss S*.

Metabolic Interdependency of Th2 Cell-Mediated Type 2 Immunity and the Tumor Microenvironment.

Front Immunol. 2021 May 31;12:632581. doi: 10.3389/fimmu.2021.632581. PMID: 34135885; PMCID: PMC8201396. *Corr. author

11. Reinhold D, Guttek K, Reddig A, Voss L, Schubert C, Kahlfuss S, Grüngreiff K, Schraven B, Reinhold A.

Zinc Aspartate Induces IL-16 Secretion and Apoptosis in Human T Cells.

Biomedicines. 2021 Mar 1;9(3):246. doi: 10.3390/biomedicines9030246. PMID: 33804583; PMCID: PMC7998552.

12. Vaeth M, Kahlfuss S, Feske S. CRAC Channels and Calcium Signaling in T Cell-Mediated Immunity.

Trends Immunology. 2020 Oct;41(10):878-901. doi: 10.1016/j.it.2020.06.012. Epub 2020 Jul 22. PMID: 32711944; PMCID: PMC7985820.

13. Kahlfuss S, Kaufmann U, Concepcion AR, Noyer L, Raphael D, Vaeth M, Yang J, Pancholi P, Maus M, Muller J, Kozhaya L, Khodadadi-Jamayran A, Sun Z, Shaw P, Unutmaz D, Stathopulos PB, Feist C, Cameron SB, Turvey SE, Feske S.

STIM1-mediated calcium influx controls antifungal immunity and the metabolic function of non-pathogenic Th17 cells.

EMBO Mol Med. 2020 Aug 7;12(8):e11592. doi: 10.15252/emmm.201911592. Epub 2020 Jul 1. PMID: 32609955; PMCID: PMC7411566.

14. Kaufmann U*, Kahlfuss S*, Yang J, Ivanova E, Koralov SB, Feske S.

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function.

Cell Metabolism. 2019 May 7;29(5):1104-1118.e6. doi: 10.1016/j.cmet.2019.01.019. Epub 2019 Feb 14. PMID: 30773462; PMCID: PMC6506368. *First-authors 

15. Woelfer M, Kasties V, Kahlfuss S, Walter M.

The Role of Depressive Subtypes within the Neuroinflammation Hypothesis of Major Depressive Disorder.

Neuroscience. 2019 Apr 1;403:93-110. doi: 10.1016/j.neuroscience.2018.03.034. Epub 2018 Mar 29. PMID: 29604382.

16. Lian J*, Cuk M*, Kahlfuss S*, Kozhaya L, Vaeth M, Rieux-Laucat F, Picard C, Benson MJ, Jakovcevic A, Bilic K, Martinac I, Stathopulos P, Kacskovics I, Vraetz T, Speckmann C, Ehl S, Issekutz T, Unutmaz D, Feske S. ORAI1 mutations abolishing store-operated Ca2+entry cause anhidrotic ectodermal dysplasia with immunodeficiency.

J Allergy Clin Immunol. 2018 Oct;142(4):1297-1310.e11. doi: 10.1016/j.jaci.2017.10.031. Epub 2017 Nov 16. PMID: 29155098;  *First-authors 

17. Kahlfuss S*, Flieger RR, Mankertz A, Yilmaz K, Roepke TK. Pericardial Tamponade in an Adult Suffering from Acute Mumps Infection. *Corr. author

Case Rep Med. 2016;2016:7980936. doi: 10.1155/2016/7980936. Epub 2016 Oct 12. PMID: 27818687; PMCID: PMC5080511.

18. Kahlfuss S*, Flieger RR, Roepke TK, Yilmaz K. Diagnosis and treatment of cardiac echinococcosis. *Corr. author

Heart. 2016 Sep 1;102(17):1348-53. doi: 10.1136/heartjnl-2016-309350. Epub 2016 May 19. PMID: 27199228.

19. Simma N, Bose T, Kahlfuss S*, Mankiewicz J, Lowinus T, Lühder F, Schüler T, Schraven B, Heine M, Bommhardt U. NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells.

Cell Commun Signal. 2014 Dec 5;12:75. doi: 10.1186/s12964-014-0075-5. PMID: 25477292; PMCID: PMC4269920. *First-authors 

20. Kahlfuss S*, Simma N*, Mankiewicz J*, Bose T*, Lowinus T, Klein-Hessling S, Sprengel R, Schraven B, Heine M, Bommhardt U. Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells. *First-authors 

Mol Cell Biol. 2014 Mar;34(5):820-31. doi: 10.1128/MCB.01273-13. Epub 2013 Dec 16. PMID: 24344200; PMCID: PMC4023824. 

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Institute of Molecular and 

Clinical Immunology

Medical Faculty

Otto-von-Guericke University

Magdeburg

Leipziger Str. 44, Building 26
39120 Magdeburg
GERMANY

Bildschirmfoto 2020-08-06 um 21.16.29.pn